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Picks against the spread

Week 4 picks · Mea culpa

George Kittle's 56-yard screen buries Broncos +3 in Santa Clara

Mea culpa

Second-highest conviction on the board, and the premise held up badly. Mike Evans played through the ribs for 5 catches and 76 yards, Brock Purdy went 19 of 30 for 218 and two scores without being sacked, and the clean Denver injury report I leaned on lost Patrick Surtain II and Riley Moss during the game. Denver did get it to 17-14 with four minutes left before George Kittle turned a screen into a 56-yard touchdown. 49ers 24, Broncos 14, so plus 3 loses by seven.

loss 49ers 24, Broncos 14

The pick: Broncos +3 at 49ers · conviction play #2

The case before kickoff

San Francisco's receiver room is down to its depth chart. Mike Evans didn't practice Wednesday with a rib injury, Demarcus Robinson is out with a high-ankle sprain, De'Zhaun Stribling is on IR after ankle surgery, and Ricky Pearsall is done for the season, so the 49ers are leaning on Jacob Cowing behind McCaffrey and Kittle. They're also missing two defensive tackles, with Thompson ruled out and West on IR. Denver's report is close to clean: Jaylen Waddle, J.K. Dobbins and Marvin Mims all practiced fully, and pass rusher Dondrea Tillman (hamstring) is the main absence. A full field goal with the healthier team is the play.

Reporting: 49ers.com takeaways · 49ersWebzone stats and notes · Bleacher Report · Denver Gazette

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